彭城 研究员，博士生导师
Email：chengpeng@ynu.edu.cn
个人简介：
彭城，博士，研究员。2011年毕业于上海交通大学，获计算机软件与理论博士学位，2008年-2010年在美国加州大学伯克利分校生物工程系进行博士联合培养。2011年进入华中农业大学生物信息系工作，2019年调入云南大学生命科学学院。主要从事生物信息学研究，开发多款生物信息学软件来处理和分析多种高通量测序数据，以通讯作者发表二十余篇学术论文。
招生专业：
生物信息学
生物化学与分子生物学
生物与医药
研究方向：
1、高通量数据分析：开发和应用生物信息学软件来处理高通量测序数据和解析生物学意义。
2、计算药物筛选：开发药物诱导扰动和药物重定位预测模型，结合实验开展初步功能验证。
代表性研究成果：（#表示共同第一作者，*通讯或共同通讯作者）
1. Yiyuli Tang, Yuzhuo Zhou, Zhenning Wei, Yan Wen, Cheng Peng*. The cell-type specific interaction based drug repurposing for psychiatric disorders. Translational Psychiatry, 2026, https://doi.org/10.1038/s41398-026-04226-9.
2. Qiang Zhang#, Qing Zhang#, Chunming Guo*, Cheng Peng*. scTumorDrug: predicting cell-type specific drug responses for heterogeneous tumors. Briefings in Bioinformatics, 2026, 27(3), bbag337.
3. Chenglong Sang, Cheng Peng*. BrainConnect: processing brain connectivity and spatial transcriptomics data for integrative analysis. Bioinformatics, 2026, 42(3), btag120.
4. Fang Liu#, Yiyu-Li Tang#, Zong-Bo Zhang, Ya-Hong Tan, Si-Hui Lin, Ni-Ya Wang, Jin-Nan Li, Zhi-Jie Pan, Jian-Feng Li, Jing-Fei Huang, Yu-Qiang Ding, Chun-Ming Guo*, Lin Xu*, Cheng Peng*, Qi-Xin Zhou*. Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer’s Disease Model at Late Stages. Advanced Science, 2026, 13(11): e06695.
5. Yang Feng#, Jie Zhou#, Dianjue Li, Zhen Wang, Cheng Peng*, Guangtao Zhu*. The haplotype-resolved T2T genome assembly of the wild potato species Solanum commersonii provides molecular insights into its freezing tolerance. Plant Communications, 2024, 5: 100980
6. Yingzhou Hong#, Kai Song#, Zongbo Zhang#, Yuxia Deng, Xue Zhang, Jinqian Zhao, Jun Jiang, Qing Zhang, Chunming Guo*, Cheng Peng*. The spatiotemporal dynamics of spatially variable genes in developing mouse brain revealed by a novel computational scheme. Cell Death Discovery, 2023, 9: 264.
7. Dan-Ya Wu#, Xinxin Li#, Qiao-Ran Sun, Cheng-Li Dou, Tian Xu, Hainan He, Han Luo, Haitao Fu, Guo-Wei Bu, Bingbing Luo, Xia Zhang, Bin-Guang Ma, Cheng Peng*, Yi-Liang Miao*. Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials. Cell Death & Disease, 2021, 12:1085.
8. Xiao-Tao Wang, Wang Cui, Cheng Peng*. HiTAD: detecting the structural and functional hierarchies of topologically associating domains from chromatin interactions. Nucleic Acids Research, 2017, 45(19): e163.
9. Xiao-Tao Wang, Peng-Fei Dong, Hong-Yu Zhang, Cheng Peng*. Structural heterogeneity and functional diversity of topologically associating domains in mammalian genomes. Nucleic Acids Research, 2015, 43(15):7237-7246.
10. Cheng Peng#*, Liang-Yu Fu#, Peng-Fei Dong, Zhi-Luo Deng, Jian-Xin Li, Xiao-Tao Wang, Hong-Yu Zhang*. The sequencing bias relaxed characteristics of Hi-C derived data and implications for chromatin 3D modeling. Nucleic Acids Research, 2013, 41(19):e183.
